Targeting Obesity through Microbiome: Update

Guest BloggerFrom The Gut, Uncategorized

feet on scale

In a world grower fatter by the day (1.9 billion overweight and obese), science is searching for answers to the pandemic. There are no easy ones. Obesity is complicated; genetics, lifestyle and the environment create an imperfect storm inside the body. Recent evidence points to the gut microbiome as one important risk factor. Indeed, the microbiome is rich in possibilities. … Read More

As Obesity Soars, Microbes Get a Closer Look

Guest BloggerFrom The Gut

Americans are getting fatter. New data from the National Health and Nutrition Examination Survey (tens of thousands surveyed) revealed stark numbers: Nearly 40% of adults are obese, up significantly from previous years. Hispanic and blacks–both adults and children– counted more obesity than whites and Asians. One other group fared especially poorly: toddlers ages 2 to 5 saw obesity rates rise, … Read More

Exercise Improves Microbe Mix in Lean People

Guest BloggerFrom The Gut

healthy people

Baby, we were born to run. Despite that innate need to move, few of us do enough exercise for optimum health. Even our microbes will vary depending on movement. For example, endurance athletes harbor different microbes than sedentary people. A new study from the University of Illinois at Urbana-Champaign tracked changes in the guts of 32 non-exercisers who started a … Read More

Fat-fighting microbes? Prove it with a robust study design.

Guest BloggerIPA In The Lab, Uncategorized

By Josh Baisley, B.Sc., Director of Clinical Trials, Nutrasource Obesity, defined as a body mass index (BMI) ≥30kg/m2, continues to be an important health issue globally, as it is a major risk factor for several diseases, including hypertension, dyslipidemia, diabetes, coronary heart disease, stroke, gall bladder disease, osteoarthritis and some cancers, among others.1,2 Rates of obesity continue to increase across … Read More

In Obesity, Prebiotics Put the Complex in Carbohydrates

Guest BloggerFrom The Gut

Obesity and its prime bedfellows (diabetes and heart disease) are epidemic. Obviously a calorie is not always just a calorie. In recent decades, science has been moving fast to discover links to microbes. Enough evidence now shows that the microbiota is different in obese and normal weight people though the details are hazy. Alert the media! Prebiotics or indigestible complex … Read More

Short-Chain Fatty Acids: Colonic Infusion Could Fight Obesity

Guest BloggerFrom The Gut

Imagine a trash collector paying you for the privilege of hauling away the junk. Not happening. But that’s what our gut microbes do: they digest the stuff we can’t—fiber—and then create short-chain fatty acids (SCFAs) which are absolute manna for our metabolic health. Note: Counterintuitively, SCFAs are handled differently than fatty acids with long carbon chains, thus removing the fat connotation from … Read More

Melatonin Unlocks a Microbial Key in Obesity

Guest BloggerFrom The Gut

A natural hormone in the body, melatonin has long been supplemented by frequent flyers to ease circadian rhythms into new time zones. A newer and potentially more valuable finding is its role in weight gain and metabolism. Indeed, melatonin reduces body weight, liver steatosis, and low-grade inflammation and improves insulin resistance in high fat diet (HFD)-fed mice. This is huge, given … Read More

Novel Microbe Targeted in Obesity: Patrice Cani PhD Reports to IPA

IPA AdminFrom The Gut

Among thousands of  weight loss strategies–mostly futile–microbes offer hope. Solid research supports the role of gut microbes in the inflammation, fat metabolism and metabolic disorders linked to obesity. Patrice Cani PhD of Brussels, Belgium shared his research on a novel new target last month at the 2016 Probiotics Symposium at Harvard. Prior studies revealed that abundance of Akkermansia muciniphila, a mucin-degrading bacterium, was inversely associated … Read More